Maternal and Infant Network to Understand Outcomes Associated with Use of Medication for Opioid Use Disorder During Pregnancy (MAT-LINK)

"The MAT-LINK [Maternal and Infant Network to Understand Outcomes Associated with Use of Medication for Opioid Use Disorder During Pregnancy] surveillance network analyzed selected demographic characteristics of pregnant persons overall and by MOUD treatment status from seven clinical sites providing data on pregnancies during 2014–2021. Of 5,541 pregnancies, 5,626 unique pregnant person–infant dyads were identified. This analysis assessed maternal characteristics across pregnancies. Among the 5,541 reported pregnancies at the seven clinical sites, 4,381 (79.1%) included persons who received MOUD (i.e., receipt of buprenorphine with or without naloxone, methadone, or naltrexone during pregnancy) and 1,160 (20.9%) included persons who did not receive any MOUD at any point during pregnancy (Table 2). The mean maternal age across all pregnancies was 29.7 (SD = ±5.1) years. Maternal race distribution was 4,607 (86.3%) White, 312 (5.8%) Black, 250 (4.7%) other races, 141 (2.6%) AI/AN, and 26 (<1.0%) Asian or NH/OPI. Among pregnant persons, 1,372 (25.4%) were Hispanic. Insurance status across various pregnancies was 4,474 (81.6%) public insurance (e.g., Medicaid), 874 (15.9%) private insurance, 125 (2.3%) no insurance, and seven (<1.0%) other insurance (including unspecified health insurance types). On the basis of RUCA code categorization using reported zip codes, 4,615 persons (84.4%) lived in or within reasonable commuting distance to urbanized areas (i.e., ≥30% of commuting flow to an area with a population of ≥50,000). Statistically significant differences were observed for all demographic characteristics except ethnicity and urbanicity evaluated between pregnant persons receiving and not receiving MOUD. Those receiving MOUD during pregnancy were more likely to be White and older and to have public insurance."