Annual Number of Deaths By Selected Causes in the US, Including Deaths Attributed to Alcohol, Tobacco, and Other Drug Use

"• In 2018, a total of 2,839,205 resident deaths were registered in the United States, yielding a crude death rate of 867.8 per 100,000 population.

"• The age-adjusted death rate, which accounts for the aging of the population, was 723.6 deaths per 100,000 U.S. standard population.

"• Life expectancy at birth was 78.7 years.

"• The 15 leading causes of death in 2018 were:
"1. Diseases of heart (heart disease)
"2. Malignant neoplasms (cancer)
"3. Accidents (unintentional injuries)
"4. Chronic lower respiratory diseases
"5. Cerebrovascular diseases (stroke)
"6. Alzheimer disease
"7. Diabetes mellitus (diabetes)
"8. Influenza and pneumonia
"9. Nephritis, nephrotic syndrome and nephrosis (kidney disease)
"10. Intentional self-harm (suicide)
"11. Chronic liver disease and cirrhosis
"12. Septicemia
"13. Essential hypertension and hypertensive renal disease (hypertension)
"14. Parkinson disease
"15. Pneumonitis due to solids and liquids"

Source: 

Murphy SL, Xu JQ, Kochanek KD, Arias E, Tejada-Vera B. Deaths: Final data for 2018. National Vital Statistics Reports; vol 69 no 13. Hyattsville, MD: National Center for Health Statistics. 2020.