"Among people aged 12 or older in 2021, 57.8 percent (or 161.8 million people) used tobacco, alcohol, or an illicit drug in the past month; 47.5 percent (or 133.1 million people) drank alcohol in the past month; 19.5 percent (or 54.7 million people) used a tobacco product in the past month; and 14.3 percent (or 40.0 million people) used an illicit drug in the past month (Figure 1 and Table A.1B). Estimates for tobacco, alcohol, or illicit drugs are not mutually exclusive because respondents could have used more than one type of substance (e.g., tobacco products and alcohol) in the past month."