Global Burden Of Cancer Attributable To Alcohol Consumption

"Globally, an estimated 741,300 (95% UI 558,500–951,200; PAF 4·1% [3·1–5·3]) of all new cases of cancer in 2020 were attributable to alcohol consumption. In males, there were 568,700 (76·7%; 95% UI 422,500–731,100; PAF 6·1% [4·6–7·9]) alcohol-attributable cancer cases, and in females there were 172,600 (23·3%; 135,900–220,100; 2·0% [1·6–2·5]) alcohol-attributable cancer cases (table). The global age-standardised incidence rate was 8·4 (95% UI 6·2–10·9) alcohol-attributable cancer cases per 100,000 people: 13·4 (10·0–17·4) cases per 100 000 males and 3·7 (2·7–5·0) cancer cases per 100,000 females.

"The cancers with the highest PAFs were cancers of the oesophagus (31·6% [95% UI 18·4–45·7]), pharynx (22·0% [9·0–37·8]), and lip and oral cavity (20·2% [12·1–32·3]), with considerable differences by sex; for example, 39·2% (22·7–55·6) of oesophageal cancers in males were attributable to alcohol, compared with 14·3% (9·0–23·5) in females. The cancer sites that contributed the most attributable cases were cancers of the oesophagus (189,700 cases [95% UI 110,900–274,600]), liver (154,700 cases [43,700–281,500]), and breast (98,300 cases [68,200–130,500]; table)."

Source: 

Rumgay, H., Shield, K., Charvat, H., Ferrari, P., Sornpaisarn, B., Obot, I., Islami, F., Lemmens, V., Rehm, J., & Soerjomataram, I. (2021). Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study. The Lancet. Oncology, S1470-2045(21)00279-5. Advance online publication. doi.org/10.1016/S1470-2045(21)00279-5