"MDMA (3,4-methylenedioxymethamphetamine; ‘ecstasy’; 'Molly', etc.) use is not uncommon in sexualized drug use [41,42].
"MDMA is not the only psychedelic phenethylamine (PIAs) molecule; others include products such as the 'fly' drugs, the toxic N-methoxybenzyl (NBOMe) compounds, indanes, and benzofurans. Recent and popular appearances in the drug scenario include several 2C-molecules, such as 2,5-dimethoxy-4-bromophenethylamine (2-CB, 'Nexus'), 2,5-dimethoxy-4-iodophenethylamine (2C-I), and 2,5-dimethoxy-4-ethylphenethylamine (2C-E). Overall, the range of MDMA-like compounds, including the NBOMes, may be purposefully or unintentionally ingested as MDMA substitutes. Most MDMA-like molecules show agonism at 5-HT2A receptors, whilst some of them also inhibit the dopamine/noradrenaline/serotonin reuptake (for an overview, see [43])."
Schifano F, Bonaccorso S, Arillotta D, et al. Drugs Used in "Chemsex"/Sexualized Drug Behaviour-Overview of the Related Clinical Psychopharmacological Issues. Brain Sci. 2025;15(5):424. Published 2025 Apr 22. doi:10.3390/brainsci15050424
